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4-Fluoroaniline

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4-Fluoroaniline Basic information
4-Fluoroaniline Chemical Properties
  • Melting point:-1.9 °C
  • Boiling point:187 °C767 mm Hg(lit.)
  • Density 1.173 g/mL at 25 °C(lit.)
  • refractive index n20/D 1.539(lit.)
  • Flash point:165 °F
  • storage temp. 2-8°C
  • solubility 33g/l
  • pka4.65(at 25℃)
  • form Oily Liquid
  • color Clear pale yellow to red-brown
  • Specific Gravity1.173
  • Water Solubility 33 g/L (20 ºC)
  • Merck 14,4169
  • BRN 742030
  • Stability:Stable. Incompatible with acids, oxidizing agents.
  • CAS DataBase Reference371-40-4(CAS DataBase Reference)
  • NIST Chemistry Referencep-Fluoroaniline(371-40-4)
  • EPA Substance Registry Systemp-Fluoroaniline (371-40-4)
Safety Information
MSDS
4-Fluoroaniline Usage And Synthesis
  • Chemical Propertieslight yellow to gold-coloured liquid
  • Uses4-Fluoroaniline is a degradation product of Ezetimibe (E975000). 4-Fluoroaniline is used as an analytical reagent in the enzymic detection of glucose.
  • UsesIntermediate in the manufacture of herbicides and plant growth regulators.
  • DefinitionChEBI: A primary arylamine that is the derivative of aniline in which the hydrogen at position 4 has been substituted by fluorine. It is used as an intermediate in the manufacture of pharmaceuticals, herbicides and plant growth regulators.
  • Synthesis Reference(s)Journal of the American Chemical Society, 70, p. 654, 1948 DOI: 10.1021/ja01182a065
    The Journal of Organic Chemistry, 26, p. 4014, 1961 DOI: 10.1021/jo01068a089
  • HazardToxic material.
  • Safety ProfilePoison by ingestion. Mutation data reported. A severe skin and eye irritant. When heated to decomposition it emits very toxic fumes of NOx and F-.
4-Fluoroaniline Preparation Products And Raw materials
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