6-Benzyl-5,7-dihydro-5,7-dioxopyrrolo[3,4-b]pyridine

89-00-9

100-46-9

18184-75-3

6-Benzyl-6H-pyrrolo[3,4-B]pyridine-5,7-dione was synthesized using 2,3-pyridinedicarboxylic acid and benzylamine as raw materials by the same method as described previously, and the reaction conditions were adjusted to react at 150 °C for 18-26 hours. After completion of the reaction, the crude product was purified using a 15 cm x 2.5 cm silica gel column with a hexane solution of 60-80% ethyl acetate as eluent. The yield of the purified product was recorded in Table 3. Special note: Saturated NH4Cl solution was used instead of 1 M HCl in the step of washing pyridine derivatives.