2,6-Dihydroxy-4-methoxyacetophenone is a phytoalexin, that can be isolated from the root tissue of Sanguisorba minor. 2,6-Dihydroxy-4-methoxyacetophenone exhibits antifungal activity. 2,6-Dihydroxy-4-methoxyacetophenone is a strong germination inhibitor on B. cinerea[1].
Obtained by reaction of boiling aqueous potassium hydroxide, on the Methyl 3-acetyl-2,4-dihydroxy-6-methoxybenzoate (quantitative yield) ; on the 3-trichloroacetyl-2,6-dihydroxy-4-methoxyacetophenone.
[1] Kokubun T, et al. 2′,6′-Dihydroxy-4′-methoxyacetophenone, a phytoalexin from the roots of Sanguisorba minor. Phytochemistry, 1994, 35(2):331-333.
