(αS,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-α-(2-methylpropyl)-4,6-Methano-1,3,2-benzodioxaborole-2-methanamine Hydrochloride is a chiral reagent used in the preparation of isocoumarin analogs as inhibitors of γ-secretase cleavage of APP. Bortezomib Impurity 37.