Basic information Description Reference Safety Related Supplier

trans-4-Aminocyclohexanol

Basic information Description Reference Safety Related Supplier
trans-4-Aminocyclohexanol Basic information
trans-4-Aminocyclohexanol Chemical Properties
  • Melting point:108-113°C
  • Boiling point:127 °C / 14mmHg
  • Density 0.9837 (rough estimate)
  • refractive index 1.4713 (estimate)
  • pka15.12±0.40(Predicted)
  • form Crystals
  • color White to almost white
  • Water Solubility Soluble in water.
  • Sensitive Hygroscopic
  • CAS DataBase Reference27489-62-9(CAS DataBase Reference)
Safety Information
MSDS
trans-4-Aminocyclohexanol Usage And Synthesis
  • DescriptionTrans-4-Aminocyclohexanol is also named as Cis-4-Aminocyclohexanol. It was a medical intermediate of ambroxol, which is used in the treatment of respiratory diseases associated with viscid or excessive mucus.1 It is used as a raw material in organic synthesis, such as in the synthesis of N-substituted 7-azabicyclo [2.2.1] hepatanes, which are good substrates for microbial oxidation of unactivated carbons by B.bassiana.2
  • Reference
    1. Y. Jian, Improved Process of the Synthesis of Trans-4-aminocyclohexanol, Fine Chemicals, 2000, vol. 2
    2. H. F. Olivo, M. S. Hemenway, M. H. Gezginci, Synthesis and Microbial Hydroxylation of Some Azabicycloalkanes, Tetrahedron Letters, 1998, vol. 39, pp. 1309-1312
  • Chemical Propertieswhite to light yellow crystal powder
  • Usestrans-4-aminocyclohexanol be used as organic intermediates.
trans-4-Aminocyclohexanol Preparation Products And Raw materials
trans-4-Aminocyclohexanol(27489-62-9)Related Product Information
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