(S)-(-)-Nadifloxacin is an anti-bacterial agent against multidrug-resistant Staphylococcus aureus. Also, it is derived from 6-Fluoro-2-methylquinoline (F595900), which is an quinoline derivative, a highly potent thrombin receptor antagonist.
Levonadifloxacin is a potent benzoquinolizine fluoroquinolone antibiotic th at is affective against Gram-positive and Gram-negative bacteria, including methicillin- and quinolone-resistant Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae, and Moraxella catarrhalis and atypical pathogens. It appears th at Levonadifloxacin targets staphylococcal DNA gyrase, unlike other quinolones, which primarily inhibit DNA topoisomerase IV.
