3-(Methylnitrosamino)propionitrile (MNPN) was detected for the 1st time in the saliva of betel quid chewers and is a potent carcinogen.
ChEBI: 3-(N-Nitrosomethylamino)propionitrile is a nitroso compound.
A nitrile. These materials are incompatible with acids; mixing nitriles with strong oxidizing acids can lead to extremely violent reactions. Nitriles are generally incompatible with other oxidizing agents such as peroxides and epoxides. The combination of bases and nitriles can produce hydrogen cyanide. Nitriles are hydrolyzed in both aqueous acid and base to give carboxylic acids (or salts of carboxylic acids). These reactions generate heat. Peroxides convert nitriles to amides. Nitriles can react vigorously with reducing agents. Acetonitrile and propionitrile are soluble in water, but nitriles higher than propionitrile have low aqueous solubility. They are also insoluble in aqueous acids.
ACUTE/CHRONIC HAZARDS: There is sufficient evidence that Propionitrile, 3-(methylnitrosamino). is an animal carcinogen.
Flash point data for Propionitrile, 3-(methylnitrosamino). are not available. Propionitrile, 3-(methylnitrosamino). is probably combustible.
Confirmed carcinogen
with experimental carcinogenic and tumorigenic data. When heated to
decomposition it emits toxic fumes of NOx.
