Chloromethyltrimethylsilane is a chemical compound belonging to the trifluoroacetic acid group. It is an essential synthetic intermediate in organic chemistry, used to prepare many types of compounds, including pharmaceuticals, agrochemicals, and dyes. The molecule consists of three silanes linked together by methylene bridges. The synthesis of Chloromethyltrimethylsilane involves reacting a mixture of hydrochloric acid and trifluoroacetic acid with methyl ketones in the presence of ethylene diamine and particles.
(Chloromethyl)trimethylsilane can be treated with aldehydes or ketones in the presence of triphenylphosphine to synthesize terminal alkenes. It can also be used in the preparation of a reagent, trimethylsilylmethyl magnesium chloride, commonly used in Peterson methylenation.
(Chloromethyl)trimethylsilane is used for Wittig reaction and building blocks.
