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GITOXIGENIN

Basic information Safety Related Supplier
GITOXIGENIN Basic information
GITOXIGENIN Chemical Properties
  • Melting point:~230 °C
  • Boiling point:435.71°C (rough estimate)
  • Density 1.0639 (rough estimate)
  • refractive index 1.6120 (estimate)
  • storage temp. −20°C
  • pka14.56±0.70(Predicted)
  • Merck 13,4445
Safety Information
  • Hazard Codes T
  • Risk Statements 23/24/25
  • Safety Statements 36/37/39-45
  • RIDADR UN 1544 6.1/PG 1
  • WGK Germany 3
  • RTECS FH5391000
  • 10
  • HazardClass 6.1(b)
  • PackingGroup III
MSDS
GITOXIGENIN Usage And Synthesis
  • Chemical Propertieslight yellow flakes
  • UsesGitoxigenin is a related compound of Digitoxigenin, which has been used in a study to assess its stereochemical effects in cancer cytotoxicity. Digitoxigenin has also been used in a study to investigate the advantage of gold(I)-catalyzed glycosidation of glycosyl o-alkyl benzoates to assemble digitoxin.
  • Biochem/physiol ActionsStructure-activity relationships for 16β-substituted digitoxigenins as inhibitors of Na+/K+ ATPases.
  • Purification MethodsRecrystallisation of gitoxigenin from aqueous EtOH produces plates of the sesquihydrate which dehydrate on drying at 100o in vacuo. It also recrystallises from Me2CO/MeOH and from EtOAc (the crystals contain 1 mol of EtOAc) with [] D +24.8o (c 1, dioxane). It has UV with max at 310, 485 and 520nm in 96% H2SO4. On heating with ethanolic HCl it yields digitaligenin with loss of H2O. [Smith J Chem Soc 23 1931, Beilstein 8 IV 2456.]
GITOXIGENIN(545-26-6)Related Product Information
GITOXIGENINSupplierMore
  • Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
  • Tel:400-660-8290 21-61259100-
  • Email:sh@meryer.com
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  • Tel:021-51320588
  • Email:tauto@tautobiotech.com
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  • Tel:0571-85361029
  • Email:synstar518@163.com
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  • Tel:400-8210725-
  • Email:product@leyan.com
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