Pale-yellow crystals. Slowly soluble in 15 parts water; soluble
in 9 parts boiling water; soluble in 110 parts alcohol
(22C). Solutions are yellow, fluorescent, and stable
to boiling.
2-Ethoxy-6,9-diaminoacridine Lactate is used in treating purulent-necrotic wounds of hooves in cattle.
Bactericide, surgical antisepsis, preparation of
pure γ-globulin.
ChEBI: Acrinol is an organic molecular entity.
A mixture of 250 parts by volume of ethylene glycol, 50 parts by weight of 6-
nitro-9-chloro-2-ethoxyacridine (obtained by reaction of 52 parts by weight of
30 nitro-4-ethoxy-diphenylamine-6-carboxylic acid with phosphorous
oxychloride), 10 parts by weight of ammonium chloride, and 11 parts by
weight of urea were heated to 170°C and stirred for 1 hour at 170°-175°C.
Subsequently, the whole was cooled to 100°C, the reaction mixture was
introduced into 1000 parts by volume of water, rendered acidic to Congo
paper by means of hydrochloric acid and the 6-nitro-9-amino-2-ethoxyacridine
precipitated was filtered off. By reduction iron according to Bechamp, 6,9-
diamino-2-ethoxy-acridine hydrochloride was obtained with yield of 83% as
the yellow needles. The base was prepared by adding an equivalent of NaOH.
MP: 124°C.
In practice it is usually used as lactate.
Antiseptic, Antibacterial
Poison by
subcutaneous, intraperitoneal, and
intravenous routes. Experimental
reproductive effects. An antiseptic. When
heated to decomposition it emits toxic
fumes of NOx.
