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cis-4-Hydroxy-L-proline

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cis-4-Hydroxy-L-proline Basic information
cis-4-Hydroxy-L-proline Chemical Properties
  • Melting point:257 °C (dec.)(lit.)
  • alpha -59 º (c=2, H2O)
  • Boiling point:242.42°C (rough estimate)
  • Density 1.3121 (rough estimate)
  • refractive index -59 ° (C=2, H2O)
  • storage temp. Store at RT.
  • solubility soluble
  • pka2.14±0.40(Predicted)
  • form Powder
  • color White to beige
  • Water Solubility soluble
  • Merck 14,4840
  • BRN 81440
  • InChIKeyPMMYEEVYMWASQN-IMJSIDKUSA-N
  • CAS DataBase Reference618-27-9(CAS DataBase Reference)
  • EPA Substance Registry SystemL-Proline, 4-hydroxy-, (4S)- (618-27-9)
Safety Information
MSDS
cis-4-Hydroxy-L-proline Usage And Synthesis
  • Chemical PropertiesWhite to beige powder
  • UsesHydroxyprolines are valuable chiral building blocks for organic synthesis of pharmaceuticals. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of trans-4- and cis-3-hydroxy-L-proline.
  • DefinitionChEBI: L-Proline in which a hydrogen at the 4-position of the pyrrolidine ring is substituted by a hydroxy group (S-configuration).
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