14-Norlanosterol, is a metabolite of Lanosterol (L174580). It is also a meiosis activating sterol (MAS), which is shown to have an important role in regulating meiosis and reproduction.
14-demethyl-lanosterol has been used to reduce cancer cell viability and increase cancer cell sensitivity to erlotinib.
ChEBI: A 3beta-sterol formed formally by loss of a methyl group from the 14-position of lanosterol.
14-demethyl-lanosterol acts as an intermediate in cholesterol biosynthesis. It is used to stimulate oocytes for meiosis. 14-demethyl-lanosterol modulates cumulus expansion.
