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Iopamidol

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Iopamidol Basic information
Iopamidol Chemical Properties
  • Melting point:>3200C (dec)
  • alpha D20 -2.01° (c = 10 in water)
  • Boiling point:740.14°C (rough estimate)
  • Density 2.0203 (estimate)
  • storage temp. -20?C Freezer
  • solubility Freely soluble in water, very slightly soluble in methanol, practically insoluble in ethanol (96 per cent) and in methylene chloride
  • pkapKa (25°) 10.70
  • form neat
  • Water Solubility 473.7g/L(25 ºC)
  • CAS DataBase Reference60166-93-0(CAS DataBase Reference)
Safety Information
  • HS Code 2924296000
  • ToxicityLD50 in mice, rats, rabbits, dogs (g/kg): 44.5, 28.2, 19.6, 34.7 i.v. (Felder); LD50 in mice (mg iodine/kg body wt): 21,800 i.v.; 20,000 i.p.; 1500 intracerebral (Felder, Pitre).
Iopamidol Usage And Synthesis
  • Chemical PropertiesWhite Crystalline Powder
  • UsesNonionic radiocontrast medium. Diagnostic aid (radiopaque medium)
  • DefinitionChEBI: A benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a (2S)-2-hydroxypropanamido group at the 5-position.
  • brand nameIsovue (Bracco).
  • General DescriptionIopamidol is a low-osmolar, nonionicmonomer with 49% organically bound iodine. It is indicatedfor use in angiography, excretory urography, andnumerous CT procedures.
Iopamidol(60166-93-0)Related Product Information
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