Allyl (3-Methylbutoxy)acetate is a colorless liquid of
strong, fruity galbanum odor with pineapple modification. It can be prepared
by reaction of chloroacetic acid with isoamyl alcohol in the presence of sodium
hydroxide and a phase-transfer catalyst, then treating the resulting sodium
amylglycolate with allyl alcohol. Allyl amylglycolate is used in fragrance
compositions, for example, for detergents.
Allyl (3-methylbutoxy)acetate may react with strong oxidizing acids sufficiently exothermically to ignite the reaction products. Also generates heat with caustic solutions. May generate flammable hydrogen with alkali metals, hydrides, and other reducing agents.
Allyl (3-methylbutoxy)acetate is combustible.
Flammability and Explosibility
Not classified
The reported median lethal concentration (LC50) for allyl (3-methylbutoxy)acetate was 0.43 mg/L (4 hour exposure) in rats. Observed sub-clinical signs in the treated rats were clear nasal discharge, ataxia, tremors, salivation, dyspnoea, hypoactivity, and slight piloerection (REACHb). The NOAEL for allyl (3-methylbutoxy)acetate was 100 mg/kg bw/day (REACHb).
