Evoxanthine is an alkaloid that has been found in O. renieri and has antimalarial and anticancer activities. It is active against P. falciparum with an IC50 value of 67.6 μg/ml. Evoxanthine decreases proliferation of nine sensitive and drug-resistant cancer cell lines (IC50s = 6.11-80.99 μM).
Uses
Evoxanthine is a compound that can be isolated from the stem bark of Pleiocarpa pycnantha[1].
References
[1] Ndongo JT, et al. Carbazole-, Aspidofractinine-, and Aspidocarpamine-Type Alkaloids from Pleiocarpa pycnantha. J Nat Prod. 2018 May 25;81(5):1193-1202. DOI:10.1021/acs.jnatprod.7b00958
![11-Methoxy-5-methyl-1,3-dioxolo[4,5-b]acridin-10(5H)-one Structure](/CAS/GIF/477-82-7.gif)
