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(R)-(+)-Ketorolac

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(R)-(+)-Ketorolac Basic information
(R)-(+)-Ketorolac Chemical Properties
  • Melting point:163-170°C
  • storage temp. Refrigerator
  • form powder
  • color white to beige
  • optical activity[α]/D +162 to +178°, c = 1 in methanol
(R)-(+)-Ketorolac Usage And Synthesis
  • Chemical PropertiesOff-White Solid
  • Uses(R)-Ketorolac is the R-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.
  • DefinitionChEBI: A 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has R configuration. Unlike the S-enantiomer, it does not exhibit COX1 and COX2 inhibition, but does exhibit analgesic activity. Racemic keto olac, known simply as ketorolac, is used (mainly as a tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis.
(R)-(+)-Ketorolac(66635-93-6)Related Product Information
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