143943-72-0
143943-72-0 性质
| 沸点 | 723.3±60.0 °C(Predicted) |
|---|---|
| 密度 | 1.44±0.1 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | 14.47±0.20(Predicted) |
143943-72-0 用途与合成方法
Benzodiazepine receptor
At all times plasma levels of Ro 41-3290, the desethylated derivative of Ro 41-3696, are higher than those of the parent drug (t max and t 1/2 values=~2 and 8 hours, respectively). Pharmacokinetics of both Ro 41-3696 and its O-desethyl metabolite Ro 41-3290 are dose proportional and time independent. Ro 41-3696 is absorbed and eliminates rapidly (time of maximum plasma concentration, approximately 1 hour; elimination half-life, approximately 2 hours). Plasma levels of Ro 41-3290 are higher than those of the parent drug, and it is more slowly eliminated (values for time of maximum plasma concentration and elimination half-life, approximately 2 and approximately 7 hours, respectively).
