去甲槟榔次碱
去甲槟榔次碱 性质
| 熔点 | 316 °C (decomp) |
|---|---|
| 储存条件 | Inert atmosphere,Room Temperature |
| 溶解度 | 在水中可溶 |
| 形态 | 固体 |
| 颜色 | 白色 |
| 水溶解性 | H2O: soluble ethanol: slightly soluble |
去甲槟榔次碱 用途与合成方法
IC50: 14 μM (human GAT-1), 39 μM (rat GAT-1), 58 μM (rat GAT-2), 119 μM (human GAT-3), 378 μM (rat GAT-3), 1870 μM (human BGT-3)
Guvacine hydrochloride is a potent inhibitor of GABA transporter, dispalys modest selectivity for cloned GABA transporters with IC 50 s of 14 μM (human GAT-1), 39 μM (rat GAT-1), 58 μM (rat GAT-2), 119 μM (human GAT-3), 378 μM (rat GAT-3), and 1870 μM (human BGT-3). Guvacine has low affinity at hBGT-1 (IC 50 >1 mM). Guvacine hydrochloride is a potent inhibitor of GABA uptake, but does not inhibit sodium-independent GABA binding, and is weak or inactive as a GABA receptor agonist. Guvacine inhibits the uptake GABA and β-alanine with IC 50 s of 23 ± 2 μM, 66 ± 11 μM in the Cat spinal cord, and 8 ± 1 μM, 123 ± 28 μM in the rat cerebral cortex, respectively.
去甲槟榔次碱 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-11-08 | HY-100809 | 去甲槟榔次碱 | 6027-91-4 | 5 mg | 600 |
| 2024-11-08 | HY-100809 | 去甲槟榔次碱 | 6027-91-4 | 10 mM * 1 mLin Water | 660 |
