Guazatine acetate salt

Guazatine is used as a seed treatment for control of Sqtoria nodorum, Tilletia caries, Fusarium spp. and Helminthosporium spp. in cereals and maize and it also acts as a bird repellent. It is also used to control Pyricularia oryzae (rice blast) and Cercuspora spp. in peanuts and soyabeans, Septoria spp. in wheat and pineapple disease in sugar cane. It is also used as a post harvest dip for seed potatoes, citrus fruit and pineapples and as a wood protectant.

ChEBI: Iminoctadine is a member of the class of guanidines that is dioctylamine in which a hydrogen from each of the terminal methyl groups is replaced by a guanidino group. Once used as a fungicidal seed dressing, it is no longer approved for use in the European Union. It has a role as an antifungal agrochemical. It is a member of guanidines, a secondary amino compound and an aliphatic nitrogen antifungal agent.

The deamidation of guazatine (GZ) is a primary mode of GZ-biotransformation in rats but is not significantly mediated by either hydrolysis or transamidation to glycine or ornithine. In photolysis, Pm is formed by photooxidation of the methylene group (probably at the 3 or 5 position). One of the minor photoproducts identified is considered to be an intermediate of Pm formation. In apple plants, the same degradation products are identified on the surface of the leaves as photodegradation products.