Anisidine exists as ortho-, meta-, and paraisomers.
They have characteristic amine (fishy) odors.
o-Anisidine hydrochloride is used as a chemical intermediate in the production of numerous azo and triphenylmethane dyes and pigments (e.g., C.I. direct red 72, disperse orange 29, direct yellow 44, direct red 24, and acid red 4); in the production of pharmaceuticals, including the expectorant guaiacol; as a corrosion inhibitor for steel; and as an antioxidant for polymercaptan resins (IARC 1999, HSDB 2009).
Gray-black crystalline solid or light gray powder. May be carcinogenic.
O-ANISIDINE HYDROCHLORIDE reacts as an acid to neutralize bases. These neutralizations generate some heat, Usually does not react as either oxidizing agents or reducing agents but such behavior is not impossible. May catalyze organic reactions.
Flash point data for O-ANISIDINE HYDROCHLORIDE are not available; however, O-ANISIDINE HYDROCHLORIDE is probably combustible.
Confirmed carcinogen
with experimental carcinogenic,
neoplastigenic, and tumorigenic data.
Mutation data reported. When heated to
decomposition it emits very toxic fumes of
NOx and HCl.
Anisidines are used in the manufacture
of azo dyes; pharmaceuticals; textile-processing chemicals
Incompatibilities: Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,bromine, fluorine, etc.); contact may cause fires or explosions.
Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides. Attacks some coatings
and some forms of plastic and rubber.
o-Anisidine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity in experimental animals.
UN2431 Anisidines, Hazard Class: 6.1; Labels:
6.1-Poisonous materials
Dissolve in combustible solvent
(alcohols, benzene, etc.) and spray solution into furnace
equipped with afterburner and scrubber, or burn spill
residue on sand and soda ash absorbent in a furnace.
