IPCONAZOLE

Ipconazole is a fungicide used in pesticide compositions.

Ipconazole controls a wide range of seed diseases in rice and other crops and is particularly effective against 'Bakanae disease', Helminthosporum leaf spot and blast on rice.

ChEBI: A member of the class of cyclopentanols carrying 1,2,4-triazol-1-ylmethyl, 4-chlorobenzyl and isopropyl substituents at positions 1, 2 and 5 respectively. Used to control a range of seed diseases in rice, vegetables and other, mainly non-food, crops.

Ipconazole is a mixture of two geometric isomer pairs (lRS,2SR,5RS) (I) and (lRS,2SR,5SR) (Ⅱ). They differ in the orientation of the hydroxy, benzyl and isopropyl groups. The ratio of I : II in the technical product is 90 : 10 and the two-component isomer pairs are of equal activity. The metabolism of ipconazole in plants and animals involves oxidation at the benzylic and isopropyl groups to yield alcohols which may be further oxidised to the corresponding ketones or carboxylic acids (or lactones).
The resulting array of metabolites can be expected to be stereochemically more complex than the original isomer mixture.

Ipconazole is stable towards hydrolysis and is thermally stable.