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Poly(L-lysine hydrobromide)

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Poly(L-lysine hydrobromide) Basic information
Poly(L-lysine hydrobromide) Chemical Properties
  • storage temp. 2-8°C
  • form lyophilized powder
  • Stability:Stable. Incompatible with strong acids, strong bases.
Safety Information
  • WGK Germany 3
  • 3-10
MSDS
Poly(L-lysine hydrobromide) Usage And Synthesis
  • Chemical Propertieswhite powder
  • Uses
    Poly-L-lysine polymers can be used in promoting cell adhesion to solid substrates, conjugation to methotrexate for increased drug transport, microencapsulation of islets, cell microencapsulation technology, microarray glass slide coating, and chromosomal preparations. It has also been used as a transfection agent for efficient labeling and to facilitate endocytosis. Lower molecular weight poly-L-lysine (30,000-70,000) is less viscuous in solution, but higher molecular weight versions provide more attachment sites per molecule.
  • DefinitionChEBI: The hydrobromide salt of poly(L-lysine).
  • General Description
    Poly-L-lysine hydrobromide is a nonspecific attachment factor in promoting cell adhesion to the substratum.
  • Biochem/physiol ActionsPoly-L-lysine is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When it is absorbed to the cell culture surface, poly-L-lysine functions to increase the number of positively charged sites available for cell binding. With cells that can digest poly-L-lysine, poly-D-lysine should be used as the attachment factor.
Poly(L-lysine hydrobromide)(25988-63-0)Related Product Information
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