NEUROPEPTIDE S (HUMAN)
NEUROPEPTIDE S (HUMAN) 用途与合成方法
EC50: 9.4 nM (neuropeptide S receptor)
Neuropeptide S human (4 pM to 1.7 nM; 48 hours) retains full agonist activity with an EC 50 of 6.7 ± 2.4 nM, the binding of [ 125I ] Y10-hNPS to CHO cells stably expressing hNPSR is saturable with high affinity (K d = 0.33 ± 0.12 nM). Neuropeptide S human (1 pM-3 μM; 48 hours) are used to compete with 0.15 nM [ 125I I] Y10-NPS, [ 125I I] Y10-NPS is displaceable by increasing concentrations of human NPS (IC 50 = 0.42 ± 0.12 nM).
Neuropeptide S human (0.1 nM-1 nM; i.c.v.) causes a significant increase in locomotor activity, the total distance traveled, percentage of time moving, number of rearing events, and center entries are also significantly increased in mice.
| Animal Model: | Male C57Bl/6 mice |
| Dosage: | 0.1 nM, 1 nM |
| Administration: | Intracerebroventricular (i.c.v.) injection |
| Result: | Increased locomotor activity and promoted wakefulness. |
NEUROPEPTIDE S (HUMAN) 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-11-08 | HY-P1389 | 1 mg | 2500 | ||
| 2024-08-19 | HY-P1389 | 5 mg | 6200 |
