ChemicalBook Product Catalog Biochemical Engineering Biochemical Reagents Biological Dyes 3-Amino-9-ethylcarbazole

3-Amino-9-ethylcarbazole

Product Name3-Amino-9-ethylcarbazole
CAS132-32-1
MFC14H14N2
MW210.27
EINECS205-057-7
MOL File132-32-1.mol

Chemical Properties

Melting point	85-88 °C(lit.)
Boiling point	355C
Density	1,15g/cm
refractive index	1.6180 (estimate)
storage temp.	2-8°C
solubility	Chloroform (Sparingly), Methanol (Slightly)
form	tablet
pka	4.99±0.30(Predicted)
color	Brown to Very Dark Brown
BRN	174969
InChI	InChI=1S/C14H14N2/c1-2-16-13-6-4-3-5-11(13)12-9-10(15)7-8-14(12)16/h3-9H,2,15H2,1H3
InChIKey	OXEUETBFKVCRNP-UHFFFAOYSA-N
SMILES	N1(CC)C2=C(C=CC=C2)C2=C1C=CC(N)=C2
CAS DataBase Reference	132-32-1(CAS DataBase Reference)
NIST Chemistry Reference	9H-carbazol-3-amine, 9-ethyl-(132-32-1)
EPA Substance Registry System	3-Amino-9-ethylcarbazole (132-32-1)

Safety Information

Hazard Codes	T
Risk Statements	25-36/37/38-40-23/24/25-45
Safety Statements	45-36/37/39-26-22-53
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	FE3590000
TSCA	TSCA listed
HazardClass	6.1
PackingGroup	III
HS Code	29339900
Storage Class	6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
Hazard Classifications	Acute Tox. 3 Oral Carc. 1B
Hazardous Substances Data	132-32-1(Hazardous Substances Data)

MSDS

Provider	Language
9-Ethylcarbazol-3-amine	English
SigmaAldrich	English
ACROS	English
ALFA	English

Usage And Synthesis

Chemical Properties

3-Amino-9-ethylcarbazole is a brownish or tannish powder and chunks. It is utilized for producing dyes and pigments, as well as serving as an indicator for peroxidase in cells and a biological stain.

Uses

3-Amino-9-ethylcarbazole (AEC) has been used as a chromogen in immunohistochemistry to visualize the cells. It has also been used as a substrate in enzyme-linked immune absorbent spot (ELISpot).

Definition

ChEBI: 3-Amino-9-ethylcarbazole is a hydrochloride salt and free amine solid compound. It has been used to visualize the bound primary antibody by using a streptavidin method. It has also been used in visualizing tissue sections from tumour samples.

Preparation

Prepared by reducing 3-nitro-N-ethylcarbazole with sodium sulfide.

General Description

Tan powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

3-Amino-9-ethylcarbazole neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.

Hazard

Questionable carcinogen; poison.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition 3-Amino-9-ethylcarbazole emits toxic fumes.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.

Safety Profile

Suspected carcinogen with experimental carcinogenic data. Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx,.

Potential Exposure

Plant workers engaged in the manufacture of this compound and its use in pigment manufacture. Laboratory workers using this material in colorimetric enzyme assays and as a biological stain

Shipping

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Incompatibilities

Waste Disposal

Incinerator equipped with a scrubber or thermal unit to reduce nitrogen oxides emissions.