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ACETARSONE

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ACETARSONE Basic information
ACETARSONE Chemical Properties
  • Melting point:220.5°C
  • Boiling point:72.17°C
  • form solid
  • pkapKa 3.73 (H2O t=26) (Uncertain);7.9 (Uncertain); 9.3(H2O) (Uncertain)
  • color Crystalline material
  • Merck 13,53
Safety Information
  • Hazard Codes T,N
  • Risk Statements 23/25-50/53
  • Safety Statements 20/21-28-45-60-61
  • RIDADR UN 3465 6.1/PG 2
  • WGK Germany 3
  • RTECS CF8400000
  • HazardClass 6.1(b)
  • PackingGroup III
  • ToxicityMLD in rabbits, cats (mg/kg): 125-150, 150-175 orally (Anderson, Leake)
MSDS
ACETARSONE Usage And Synthesis
  • Usesantiprotozoal; diethylamine salt as antiphilitic
  • brand name190 f;Acetarsolum;Amarson;Arsabott;Auryphan;Chrlich 594;Collarsin;Edoiacolo;Ehrlich 594;F 190;Fluryl;Fourneau 190;Kharophene;Neo-vagex;Pallacid;Trichovan;Vagipurin;Vagisep;Vagival.
  • World Health Organization (WHO)Acetarsol, which has antiprotozoal and antitrichomonal activity, has largely been discarded for systemic use because of its potential to cause systemic poisoning. However, topical preparations for vaginal trichomoniasis are still available and it is included in low concentrations (equal to or less than 0.45%) in some medicated toothpastes.
  • Safety ProfilePoison by ingestion and intravenous routes. Human systemic effects by ingestion: respiratory system, endocrine system, dermatitis, and fever. Human systemic effects by intravagmal route: hallucinations, dlstorted perceptions, convulsions, nausea or vomiting, decreased urine volume, and fever. Mutation data reported. See also ARSENIC COMPOUNDS. When heated to decomposition it emits very toxic fumes of NOx, and As
  • Purification MethodsIt crystallises from water in colourless prisms. It decomposes slowly on prolonged boiling in H2O or dilute alkalis. The N-propionyl derivative recrystallises from H2O with m 228-229o(dec). [Raiziss & Fisher J Am Chem Soc 48 1323 1926, Hewitt & King J Chem Soc 823 1926, Beilstein 16 I 491, 16 II 521, 16 III 1129.]
ACETARSONE Preparation Products And Raw materials
ACETARSONE(97-44-9)Related Product Information
ACETARSONESupplierMore
  • Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
  • Tel:18930552037 821-50328103-801
  • Email:3bsc@sina.com
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  • Tel:1-(800)-881-8210
  • Email:inquiries@lgmpharma.com
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  • Company Name:Shanghai TaoSu Biochemical Technology Co., Ltd.
  • Tel:021-33632979
  • Email:info@tsbiochem.com
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  • Company Name:Tianjin heowns Biochemical Technology Co., Ltd.
  • Tel:400 638 7771
  • Email:sales@heowns.com
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  • Company Name:Beijing Minruida Technology Co., Ltd.
  • Tel:010-82387566 010-82387566-
  • Email:sales@mreda.com.cn
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