Tylosin Tartrate is a macrolide antibiotic isolated from a strain of Streptomycetes fradiae found in soil from Thailand. Antibacterial.
Tylosin tartrate is used as chemotherapeutic agent used to treat pigs with enteritis, household pets with respiratory infections and mastitis in cows.
Tylosin tartrate is a macrolide antibiotic approved for the control of mycoplasmosis in poultry
Tylosin tartrate (10-500 mg/kg; s.c.) generally suppresses the elevated TNF-α and IL-1β levels and increases the IL-10 levels in the Lipopolysaccharide (LPS) -treated animals[4].
| Animal Model: | Balb/C mice (2-3 months old, 20-25 g)[4] |
| Dosage: | 10 mg/kg, 100 mg/kg, 500 mg/kg |
| Administration: | Subcutaneous injection |
| Result: | Reduced the elevated TNF-α and IL-1β in LPS (250 μg)-treated mice but increased their IL-10 levels. |
