Cesium carbonate is an inorganic compound. It is a white solid under normal temperature and pressure. It is easily soluble in water and quickly absorbs moisture when placed in the air. Cesium carbonate aqueous solution is strongly alkaline and can react with acid to produce corresponding cesium salt and water, and release carbon dioxide. Cesium carbonate is easy to transform, can be used as a precursor of other cesium salts, and is a widely used cesium salt.
Cesium carbonate can be used as a modified layer between the active layer of the solar cell and the Al electrode to improve the conversion efficiency of the device, generate Al-O-Cs compounds, reduce the series resistance of the battery, and improve the short-circuit current and photoelectric conversion efficiency of the solar cell, and Due to the compactness of the cesium carbonate layer itself, the stability of the device has also been significantly improved. The strong metallic n-type heavy doping effect of cesium in cesium carbonate, the Al/CsCO cathode modified with cesium carbonate nano-interface can greatly increase the injection of electrons, and significantly improve the performance of the inverted top-emitting structure OLED device. Cesium carbonate is also used as a catalyst for the synthesis of alkyl aryl ethers.
The method of preparing cesium carbonate using cesium alum as a raw material :1. To recrystallize cesium alum, add cesium alum in deionized water and heat to dissolve, after dissolving, cool to crystallize and filter, and obtain refined cesium alum after filtering;2. Transformation, add refined cesium alum in deionized water and heat to dissolve, obtain refined cesium alum solution after dissolving, slowly drip lime milk into refined cesium alum solution, and obtain cesium sulfate net solution after solid-liquid separation;3. Causticizing, the barium hydroxide solution is added to the cesium sulfate clean liquid in 2 to 3 times, and the barium sulfate solid and the causticizing liquid are obtained by centrifugal separation;4. Carbonization, concentration and evaporation, pass CO into the causticizing solution for carbonization, carbonize until the pH of the carbonization solution is 7 to 10, stand still, concentrate the carbonization supernatant after standing, and obtain a concentrated solution after cooling;5. Once fine filtration and drying, the concentrated liquid is filtered with a polymer filter device, the filtered filtrate is concentrated and crystallized and dried at low temperature to obtain a low-temperature material;6. High temperature decomposition, after high temperature decomposition of low temperature material, high temperature material is obtained;7. Secondary fine filtration, the high temperature material is dissolved in deionized water, and then filtered with a polymer filter device, and the filtered liquid is obtained after filtration;8. The clean liquid is concentrated and dried, and the filtered clean liquid is concentrated and dried to obtain cesium carbonate.
Cesium carbonate is a basic carbonate and is used in organic synthesis as a mild inorganic base. It can be used in C, N, O alkylation and arylation reactions. Cesium carbonate not only promotes the carbonylation of alcohols and carbamination of amines but also inhibits side reactions common in other processes. It is also used in six-membered annulation, intramolecular and intermolecular cyclizations, Suzuki coupling, aza-Henry, nucleophilic substitution, cross-coupling and different cycloaddition reactions.
Colourless crystals or white powder , easily soluble in water, quickly absorbs moisture when placed in the air. The aqueous solution of cesium carbonate is strongly alkaline and can react with acid to produce the corresponding cesium salt and water, and release carbon dioxide.
Cesium carbonate is a versatile reagent for organic synthesis. This inorganic base has been employed in numerous organic applications ranging from N-protection of amino acids to a base in either the Horner- Wadsworth-Emmons reaction or in Suzuki couplings. It has also found use as a catalyst for ethylene oxide polymerization, in coating for spatter-free welding of steel in CO2, as a functional interlayer in photovoltaic devices and in oxide cathodes. Cesium carbonate is also used in the beer-brewing industry to make the "head" of beer foamier.
cesium carbonate can be prepared by thermal decomposition of caesium oxalate. Upon heating, caesium oxalate is converted to caesium carbonate with emission of carbon monoxide.
Cs2C2O4 → Cs2CO3 + CO
It can also be synthesized by reacting caesium hydroxide with carbon dioxide.
2 CsOH + CO2 → Cs2CO3 + H2O
Cesium carbonate is widely utilized as a precursor for other cesium compounds. It acts as a base in sensitive organic reactions. It can be used as a base in C-C and C-N cross-coupling reactions such as SuzukiMiyaura, Heck, and Buchwald-Hartwig amination reactions. It finds use in solar cells as it increases the power conversion efficiency of cells through the transfer of electrons. It is also used in the production of special optical glasses, petroleum catalytic additives, special ceramics and in the sulfuric acid industry. It is useful in the N-alkylation (of sulfonamides, beta-lactams, indoles, heterocycles and several sensitive nitrogen compounds), carbamination of amines, carbonylation of alcohols and aerobic oxidation of alcohols into carbonyl compounds without polymeric by products. Promotes the efficient O-alkylation of alcohols to form mixed alkyl carbonates.
The numerous properties of caesium carbonate in organic synthesis stem from the relatively weak Lewis acidity of the caesium ion, enabling its solubility in organic solvents such as alcohols, DMF, and diethyl ether. Caesium carbonate serves as an effective inorganic base in numerous palladium-catalysed reactions, including the Heck, Suzuki, and Sonogashira reactions. As shown in Equation 1 [1], the Suzuki cross-coupling reaction achieves an 86% yield when facilitated by caesium carbonate. However, the same reaction yields only 29% and 50% when using sodium carbonate or triethylamine, respectively. In the Heck reaction between methacrylates and chlorobenzene, caesium carbonate demonstrates markedly superior performance compared to other inorganic bases (e.g., potassium carbonate, sodium acetate, triethylamine, potassium phosphate) (Equation 2 [2]).
Inorganic bases include LiOt Bu, NaOt Bu, NaOAc, LiOH, NaOH, KOH, Na2CO3, K2CO3, Cs2CO3, ect. Organic bases include DBU and Et3N, etc. Cesium carbonate has a similar basicity with DBU. Due to the poor solubility of most inorganic bases in organic solvents and the aggregation between metal ions and solvent molecules, which may cause some side-effect to the basicity of bases. The solubility of metal carbonate in dipole aprotic solvents is shown below.
In the transition metal catalytic organic reactions, different bases were chosen in the palladium catalyzed reaction system, leading to a sharp change in reaction yields. In the direct carboxylation of indole mediated by LiOt Bu. Cs2CO3 as a strong base enhanced reaction yield dramatically, while K2CO3 as a weak base can only generate very little carboxyl products. The most commonly used bases in Suzuki reactions are Na2CO3, Cs2CO3, potassium acetate, potassium phosphate etc[1]. The reactive order of alkali carbonates are as follows: Cs2CO3 > K2CO3 > Na2CO3 > Li2CO3. Caesium carbonate facilitates the N-alkylation of compounds such as sulfonamides, amines, β-lactams, indoles, heterocyclic compounds, N-substituted aromatic imides, phthalimides, and other similar compounds.
Cesium carbonate is a powerful inorganic base widely used in organic synthesis. It is a potential chemoselective catalyst for the reduction of aldehydes and ketones to alcohols. It is employed as base for the Heck coupling reaction of 4-trifluoromethyl-1-chlorobenzene and aryl chlorides.
Cesium carbonate is a danger compound.
H315: Causes skin irritation
H318: Causes serious eye damage
H335: May cause respiratory irritation
H361: Suspected of damaging fertility or the unborn child
H373: May cause damage to organs through prolonged or repeated exposure
Flammability and Explosibility
Non flammable
Moderately toxic by
ingestion. Mutation data reported. When
heated to decomposition it emits acrid
smoke and fumes. See also CESIUM.
Crystallise it from ethanol (10mL/g) by partial evaporation. [D.nges in Handbook of Preparative Inorganic Chemistry (Ed. Brauer) Academic Press Vol I p 988 1963.]
[1] Guo L, et al. Applications of Bases in Transition Metal Catalyzed Reactions
Zhao Yuan. Chemistry - A European Journal, 2018; 24: 7794-7809.
