PEI PrimeTM is a cationic polymer designed for high-yield, reproducible and scalable drug and gene delivery. As a gene carrier, PEI forms a complex with nucleic acids via electrostatic self-assembly between the negatively charged nucleic acid phosphate groups and positively charged PEI amine groups. Due to this interaction, PEI has been extensively explored as a gene carrier and is one of the most effective synthetic polymers for the delivery of nucleic acids into cells through endocytosis.
PEI PrimeTM uses an optimized form of PEI to reduce performance variance and speed process development time. Each batch of PEI PrimeTM undergoes triplicate, quantitative performance testing using an SEAP reporter assay. PEI PrimeTM is an excellent choice to produce any biologic cost-effectively, including recombinant proteins, antibodies, and viruses.
