Taxiresinol (100 mg/kg, oral administration, once) shows significant antinociceptive activity against p-benzoquinone-induced abdominal contractions in mice[1].
| Animal Model: | Male Swiss albino mice (20-25 g)[1] |
| Dosage: | 100 mg/kg |
| Administration: | Oral administration, sixty minutes after the oral administration of test sample, the mice were intraperitoneally injected with 0.1 ml/10 g body weight of 2.5% (v/v) p-benzoquinone solution in distilled H2O. |
| Result: | Showed significant antinociceptive activity against p-benzoquinone-induced abdominal contractions (writhing movements) in mice, with a inhibitory ratio of 37.8%. |
![4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol Structure](/CAS/GIF/40951-69-7.gif)