yellow crystals or gold liquid
N-Nitrosomorpholine, a frequently used genotoxic model carcinogen. Toxicogenomic analysis of N-Nitrosomorpholine induced changes in rat liver.
Solvent for polyacrylonitrile; present
during rubber manufacturing
ChEBI: A nitrosamine that is morpholine in which the hydrogen attached to the nitrogen is replaced by a nitroso group. A carcinogen and mutagen, it is found in snuff tobacco.
Yellow crystals. Golden liquid with many crystals at 68°F.
N-NITROSOMORPHOLINE is incompatible with strong oxidizing agents .
ACUTE/CHRONIC HAZARDS: When heated to decomposition N-NITROSOMORPHOLINE emits toxic fumes of nitrogen oxides.
Flash point data for N-NITROSOMORPHOLINE are not available; however, N-NITROSOMORPHOLINE is probably combustible.
Tumor initiator in rodent liver, trachea, nasal cavity, esophagus, kidney, lung, and thyroid.
Confirmed carcinogen
with experimental carcinogenic,
neoplastigenic, and tumorigenic data. Poison
by ingestion, intraperitoneal, subcutaneous,
and intravenous routes. Moderately toxic by
inhalation. Human mutation data reported.
Experimental reproductive effects. When
heated to decomposition it emits toxic
fumes of NOx. See also N-NITROSO
COMPOUNDS.
N-Nitrosomorpholine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
