Trocinate,Poythress,US,1950
The following procedure is described in US Patent 2,510,773: To an ice-cold
solution of 13.3 grams of 2-diethylaminoethanethiol in 100 cc of dry benzene
is slowly added a solution of 23.05 grams of diphenylacetyl chloride in 200 cc
of dry benzene. The mixture is stirred 2 hours, then heated to dissolve the
fine white solid that is formed. Upon cooling 31.3 grams of 2-
diethylaminoethyl diphenylthiolacetate hydrochloride precipitates. It
recrystallizes from a mixture of benzene and petroleum ether (BP 60° to
70°C) as rosettes of tiny needles and melts at 129° to 130°C. From a mixture
of absolute ethanol and ethyl acetate it recrystallizes as large, almost
transparent prisms.
