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D-Proline

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D-Proline Basic information
D-Proline Chemical Properties
  • Melting point:223 °C (dec.)(lit.)
  • alpha 84.75 º (c=4, H2O)
  • Boiling point:215.41°C (rough estimate)
  • Density 1.36
  • refractive index 85 ° (C=4, H2O)
  • storage temp. Store at RT.
  • pka1.952(at 25℃)
  • form Powder
  • color White to yellow to pale brown
  • optical activity[α]22/D +85.0°, c = 4 in H2O
  • Water Solubility soluble >1000 g/L (20 ºC)
  • Sensitive Hygroscopic
  • BRN 80811
  • InChIKeyONIBWKKTOPOVIA-SCSAIBSYSA-N
  • CAS DataBase Reference344-25-2(CAS DataBase Reference)
  • EPA Substance Registry SystemD-Proline (344-25-2)
Safety Information
MSDS
D-Proline Usage And Synthesis
  • Chemical PropertiesWhite to off-white powder
  • UsesUsed in the synthesis of (R)-(+)-N-Boc-Pipecolic Acid, (S)-(-)-Coniine, (S)-(+)-Pelletierine, (+)-.beta.-Conhydrine, and (S)-(-)-Ropivacaine and formal synthesis of (-)-Lasubine II and (+)-Cermizine C.
  • UsesLabelled D-Proline Lasubine II and (+)-Cermizine C.
  • Usesproline is a skin-conditioning agent. An amino acid found in the collagen molecule.
  • DefinitionChEBI: The D-enantiomer of proline.
  • Synthesis Reference(s)Journal of the American Chemical Society, 71, p. 2818, 1949 DOI: 10.1021/ja01176a065
    Tetrahedron Letters, 28, p. 6469, 1987 DOI: 10.1016/S0040-4039(00)96890-4
D-Proline Preparation Products And Raw materials
D-Proline(344-25-2)Related Product Information
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