Diazolidinyl urea was first introduced in 1982 (Sutton Labs, Chatham, New Jersey). It is a colorless, odorless, stable, and water-soluble preservative. It is reported to have a wider antimicrobial spectrum than imidazolidinyl urea, which is structurally related. It is effective against gram-negative and gram-positive bacteria, molds, and yeast but has limited activity against fungi. Diazolidinyl urea, a formaldehyde re1easer, is mainly contained in cosmetics and toiletries, and can be found in barrier creams.
2,5-Diazolidinylurea is a preservative used in cosmetic creams, lotions, shampoos, hair gels, etc.
diazolidinyl urea is an antiseptic and deodorizer. It is also a broadspectrum preservative against bacteria and fungi. generally, it is used in concentrations of 0.03 to 0.3 percent. It has been found that diazolidinyl urea is a stronger sensitizer than imidazolidinyl urea for people sensitive or allergic to formaldehyde.
ChEBI: Diazolidinylurea is an imidazolidine-2,4-dione.
Flammability and Explosibility
Non flammable
Diazolidinyl urea, a formaldehyde releaser, is contained mainly in cosmetics and toiletries and can be found in barrier creams.
The Cosmetic Ingredient Review Expert Panel evaluated the safety of diazolidinyl urea and found that the ingredient is safe for current uses and concentrations, and it has low eye irritation potential. However, it has not been found to be sensitive to the skin or produce phototoxic effects. It’s use is restricted to maximum concentrations of 0.5%. This limit in concentration is mostly due to mild irritation that can occur on the skin in concentrations greater that this maximum.
