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Mubritinib

Basic information Safety Related Supplier
Mubritinib Basic information
Mubritinib Chemical Properties
  • Melting point:158.0 to 162.0 °C
  • Boiling point:620.9±65.0 °C(Predicted)
  • Density 1.25±0.1 g/cm3(Predicted)
  • storage temp. Store at +4°C
  • pka1.45±0.10(Predicted)
  • CAS DataBase Reference366017-09-6
Mubritinib Usage And Synthesis
  • UsesTreatment of cancer.
  • Biological ActivityPotent, irreversible human epithelial growth factor receptor 2 (ErbB2) inhibitor (IC 50 = 6 nM) that displays > 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src. Exhibits potent antiproliferative effects in ErbB2-overexpressing cancer cell lines (IC 50 = 5 nM in BT474 breast cancer cells) and significantly inhibits bladder, breast and prostate cancer xenograft growth in vivo .
Mubritinib(366017-09-6)Related Product Information
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