Thonzylamine is a selective H1-histamine receptor anatagonists. Tropine esterase inhibitor.
ChEBI: N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-(2-pyrimidinyl)ethane-1,2-diamine is a member of methoxybenzenes.
An oily liquid. Used (in the form of the hydrochloride) as an antihistaminic.
thonzylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
ACUTE/CHRONIC HAZARDS: Toxic. Hazardous decomposition products.
Thonzylamine is synthesized by treating
the sodium salt of 2-(4-methoxybenzyl)aminopyrimidine
with N,N-dimethyl-2-chloroethylamine
.
