N-(m-PEG4)-N'-(biotin-PEG3)-Cy5 is a PEG linker containing a cyanine dye with excitation/emmission maximum 649/667 nm as well as biotin, which enables efficient protein enrichment. The hydophilic PEG spacer increases solubility in aqueous media.
Uses
N-(m-PEG4)-N'-(biotin-PEG3)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005