C3a (70-77) TFA
中文名称:C3a (70-77) TFA
英文名称:C3a (70-77) TFA
CAS号:
分子式:C??H??F?N??O??
分子量:0
EINECS号:
Mol文件:Mol File
C3a (70-77) TFA 用途与合成方法
C3a (70-77) TFA (Complement 3a (70-77) TFA) 是对应于 C3a 的 COOH 末端的八肽,表现出 C3a 的特异性和 1 至 2% 的生物活性。
The direct interaction of C3a(70-77) with human mononuclear leukocytes in culture results in a concentration-dependent inhibition of the generation of LIF evoked by mitogens and by the antigen SK-SD.
C3a (70-77) induces histamine release and degranulation of rat mast cells, promotes contraction of guinea pig ileal tissue, and enhances vascular permeability in human skin. C3a (70-77) selectively desensitizes ileal smooth muscle to C3a but not to human C5a, a related anaphylatoxin. The cross-desensitization indicates a specific interaction of C3a (70-77) with cellular C3a binding sites.