6-Hydroxygenistein is a genotoxic by targeting topoisomerase-II (TOPII). Oxidative metabolism of 6-Hydroxygenistein is also shown to generate hydroxylated metabolites with catecholic structures, which is applied to human colon carcinoma cells.
Definition
ChEBI: 5,6,7,4'-Tetrahydroxyisoflavone is a member of isoflavones.