Phenylpiperazines are entactogenic drugs which direct central serotonin release. Substituted phenylpiperazines, such as 1-(3-chlorophenyl)piperazine, have been identified as designer drugs or drugs of abuse. 1-(4-Fluorophenyl)piperazine dihydrochloride is a substituted phenylpiperazine with a potential for abuse. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications.
1-(4-Fluorophenyl)piperazine is a major metabolite of Niaparazine, a sedative, hypnotic drug. Metabolites of Niaprazine occurred by N-dealkylation, N-dearylation, aromatic hydroxylation and N-oxidation.
