HSD17B13-IN-46 (Compound 351) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of < 0.1 μM for estradiol. HSD17B13-IN-46 can be used for research on liver diseases or metabolic disorders[1].
References
[1] Wang G, et al. 17-beta-hydroxysteroid dehydrogenase type 13 inhibitors and methods of use thereof. U.S. , WO2023023310. 2023-5-11.
