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Mupirocin

Product NameMupirocin

CAS12650-69-0

MFC26H44O9

MW500.62

EINECS603-145-3

MOL File12650-69-0.mol

Chemical Properties

Melting point 77-780C
alpha  D20 -19.3° (c = 1 in methanol)
Boiling point 672℃
Density  1.183±0.06 g/cm3(Predicted)
Flash point >110°(230°F)
storage temp.  Inert atmosphere,Store in freezer, under -20°C
solubility  H2O: 12 mg/mL, soluble
form  solid
pka 4.78±0.10(Predicted)
color  white to tan
optical activity [α]/D -15.7 to -20°, c = 1 in methanol
Water Solubility  Soluble in DMSO or methanol. Sparingly soluble in water
λmax 222nm(EtOH)(lit.)
Merck  14,6302
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey MINDHVHHQZYEEK-HBBNESRFSA-N
CAS DataBase Reference 12650-69-0(CAS DataBase Reference)

The crude drug of Bactroban ointment produced by the well-known domestic pharmaceutical company SmithKline is mupirocin which is a new type of local topical antibiotic and a kind of metabolic substance produced in the culture solution of pseudomonas fluorescence, that is, Pseudomonas A. Mainly through reversibly combined with isoleucine transfer RNA synthetase, this product can prevent the isoleucine incorporation and terminate the protein synthesis in cells containing isoleucine, leading to bacterial death.

Safety Information

WGK Germany  2
RTECS  RA6907000
HS Code  2941906000

Usage And Synthesis

Preparation Products And Raw materials

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