Basic information Feature reaction of phloroglucinol Chemical properties Uses Production method Hazards & Safety Information Safety Related Supplier
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Basic information Feature reaction of phloroglucinol Chemical properties Uses Production method Hazards & Safety Information Safety Related Supplier
Phloroglucinol Basic information
Phloroglucinol Chemical Properties
  • Melting point:215-220 °C
  • Boiling point:194.21°C (rough estimate)
  • Density 0.801 g/mL at 20 °C
  • refractive index n20/D 1.365
  • Flash point:14 °C
  • storage temp. Store below +30°C.
  • solubility Soluble in diethyl ether, ethanol and pyridine.
  • pkapK1:8.45(0);pK2:8.88(-1) (25°C)
  • form Crystalline Powder
  • color White to light beige
  • Water Solubility 11.17g/L(room temperature)
  • Sensitive Light Sensitive & Hygroscopic
  • Merck 14,7328
  • BRN 1341907
  • CAS DataBase Reference108-73-6(CAS DataBase Reference)
  • NIST Chemistry Reference1,3,5-Benzenetriol(108-73-6)
  • EPA Substance Registry System1,3,5-Benzenetriol (108-73-6)
Safety Information
Phloroglucinol Usage And Synthesis
  • Feature reaction of phloroglucinolReaction of formaldehyde with phloroglucinol under alkaline conditions generates orange compound. The colorimetric assay determination of this compound at the maximum absorption wavelength of 460 nm, can be used to detect low or trace formaldehyde in textile and garment.
    Since phloroglucinol may occur enol and keto tautomers, it can react with ammonia according following reaction:
    Under the influence of ammonia, 1,3,5-Benzenetriamine can be obtained by keto reaction of phloroglucinol
    Under the influence of ammonia, 1,3,5-Benzenetriamine can be obtained by keto reaction of phloroglucinol, while this amine can also hydrolyze in aqueous acid to generate phloroglucinol. Besides phloroglucinol can also have enol reaction.
    phloroglucinol can also have enol reaction
    The information above is edited by Andy from Chemicalbook.
  • Chemical propertiesThis product is a white or light yellow crystal or crystalline powder with melting point of 218 ℃. Usually it carries two molecular crystallization water ([6099-90-7]) and converts into anhydrous at 110 ℃. It can be dissolved in 100 parts of water, 10 parts of ethanol, and 0.5 parts of pyridine and is soluble in ether. Besides It partially decomposes when sublimation, and changes its color when exposed to the light. In addition it tastes sweet.
  • UsesIt can be used in verifications of antimony, arsenic, cerium, chromate, chromium, gold, iron, mercury, nitrites, osmium, palladium, tin, vanadium, vanillin and lignin, and measurement of furfural, pentose, pentosan, methanol, chloral hydrate, turpentine, Lignified cell tissues, free acid in gastric juice (HCl) and decalcified bone specimens. Besides it can also be used as biological reagent dyes.
  • Production method2,4,6-aminobenzoic acid can be obtained by 2,4,6-trinitrobenzoic acid`s reduction of zinc particles. After its dilute solution was heated at reflux for 20h, acidified with hydrochloric acid, cooled and crystallized, phloroglucinol can be obtained with a yield of 46-53%.
  • Hazards & Safety InformationCategory: Toxic substances
    Toxicity grade: Moderate toxicity
    Acute toxicity: oral-rat LD50: 4000 mg/kg; Oral-Mouse LD50: 4550 mg/kg
    Flammability hazard characteristics: Combustible fire burning can cause smoke irritation
    Storage characteristics: Ventilated, low-temperature and dry warehouse; and separately with oxidants
    Extinguishing agents: Carbon dioxide, foam, sand and water mist
  • Chemical Propertieswhite to light yellow crystal
  • UsesAntispasmodic.
  • UsesPhloroglucinol (1,3,5-trihydroxybenzene) is the core structure of a large family of substituted phenolics with broad, albeit weak, biological activity. Phloroglucinol is a useful metabolite for HPLC/DAD and bioassay dereplication.
  • Usesdiagnostic aid growth hormone releasing factor
  • UsesA potentially useful hygroscopic biochemical.
  • DefinitionChEBI: A benzenetriol with hydroxy groups at position 1, 3 and 5.
  • Safety ProfileModerately toxic by subcutaneous and intraperitoneal routes. Mildly toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. Used in diazo-type printing and textile dyeing, in microscopy as a bone specimen decalcifier
  • Purification MethodsCrystallise the triol from water, and store it in the dark under nitrogen. [Beilstein 6 IV 7361.]
Phloroglucinol Preparation Products And Raw materials
Phloroglucinol(108-73-6)Related Product Information
  • Company Name:-Jiangsu Dingye Pharmaceutical Co., Ltd. Gold
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  • Products Intro:CAS:108-73-6
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  • Products Intro:CAS:108-73-6
  • Company Name:Taixing Haorui Technology Co., Ltd. Gold
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  • Products Intro:CAS:108-73-6
  • Company Name:Wuhan xinyangruihe Chemical Technology Co., Ltd. Gold
  • Tel:18120580375 027-83850375-
  • Products Intro:Product Name:Phloroglucinol
    Purity:98%;99% Package:1公斤;25公斤;100公斤;吨位
  • Company Name:East Star Biotech (Suzhou) Co., Ltd. Gold
  • Tel:17706846989 0512-62620298-
  • Products Intro:Product Name:Phloroglucinol
    Purity:99%Min. Package:25KG Remarks:1