ChemicalBook > Product Catalog > Biochemical Engineering > Protein Research > Protease inhibitors > TPCK
TPCK
- Product Name:TPCK
- CAS:402-71-1
- MF:C17H18ClNO3S
- MW:351.85
- EINECS:206-954-6
- Mol File:402-71-1.mol
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TPCK Chemical Properties
- Melting point:106-108 °C(lit.)
- Boiling point:509.9±60.0 °C(Predicted)
- Density 1.1350 (rough estimate)
- refractive index 1.6100 (estimate)
- storage temp. −20°C
- solubility DMSO: >10 mg/mL stable for several months at 4°C.
- pka8.71±0.50(Predicted)
- form powder
- color white
- BRN 2895215
- CAS DataBase Reference402-71-1
- EPA Substance Registry SystemBenzenesulfonamide, N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-4-methyl- (402-71-1)
- Language:EnglishProvider:SigmaAldrich
- Language:EnglishProvider:ACROS
TPCK Usage And Synthesis
- Chemical Propertieswhite crystalline powder
- UsesN-α-Tosyl-L-phenylalanylchloromethane is a proteinase inhibitors with apoptotic function. Studies have shown that it induces caspase-dependent apoptosis in Epstein-Barr virus (EBV)-transformed human B cell lines with release of pro-apoptotic proteins from mitochondria. It also results in down-regulation of the anti-apoptotic proteins and caspase-dependent cleavage of two anti-apoptotic proteins. I t promotes dephosphorylation of p53 on serine residues.
- DefinitionChEBI: The N-tosyl derivative of L-phenylalanyl chloromethyl ketone.
- Safety ProfileExperimental reproductive effects. A flammable liquid. When heated to decomposition it emits toxic fumes of NOx, SOx, and Cl-.
- N-BOC-L-leucylglycyl-arginine-p-nitroanilide hydrochloride Ethyl N-benzoyl-L-tyrosinate BAA TOS-ARG-OME HCL TLCK N-Benzoyl-DL-arginine-4-nitroanilide hydrochloride Ethyl N-benzoyl-L-argininate hydrochloride BUTEIN Trypsin, TPCK treated, bovine pancreas,TRYPSIN TYPE XIII TPCK TREATED*FROM BOVI NE PANCREAS,TRYPSIN, TPCK TREATED, F. BOVINE PANC., ~7500 U/MG,TRYPSIN TPCK TREATED FROM BOVINE*PANCREA S ASEPTICAL TRYPSIN TPCK TREATED FROM BOVINE PANCREA IMMOBILIZED TRYPSIN, TPCK,TPCK TRYPSIN,TRYPSIN, TPCK TREATED TPCK-TRYPSIN AGAROSE TPCK TRYPSIN, TPCK TREATED, FROM BOVINE PANCREAS TRYPSIN FROM BOVINE PANCREAS TPCK TREATE
TPCKSupplierMore
- Company Name:J & K SCIENTIFIC LTD.
- Tel:400-666-7788 010-82848833-
- Email:jkinfo@jkchemical.com;market6@jkchemical.com
- Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel:400-660-8290 21-61259100-
- Email:sh@meryer.com
- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:18930552037 821-50328103-801
- Email:3bsc@sina.com
- Company Name:TCI (Shanghai) Development Co., Ltd.
- Tel:021-67121386 / 800-988-0390
- Email:Sales-CN@TCIchemicals.com
- Company Name:Energy Chemical
- Tel:400-005-6266 021-58432009
- Email:sales8178@energy-chemical.com