RO 106-9920
62645-28-7 Basic informationMore
- Product Name:RO 106-9920
- Synonyms: RO 106-9920 TETRAZOLOPYRIDAZINE-PHENYLSULFOXIDE 6-(PHENYLSULFINYL)TETRAZOLO[1,5-B]PYRIDAZINE Tetrazolo[1,5-b]pyridazine, 6-(phenylsulfinyl)- Ro 106-9920 DISCONTINUED Ro 106 9920,Ro 1069920
- CAS:62645-28-7
- MF:C10H7N5OS
- MW:245.26
- EINECS:
- Mol File:62645-28-7.mol
-
USE
Ro 106-9920 is an inhibitor of NF-κB activation, possibly via selective inhibition of LPS- and TNF-α-induced IκBα ubiquitination (IC50 = 3 μM). Ro 106-9920 blocks subsequent production of TNF-α, IL-1β and IL-6. Inhibits mucin production in an in vitro model of COPD, and is anti-inflammatory following oral administration in vivo. Also weakly inhibits EGFR, 5-lipoxygenase and iNOS.
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:Ro 106-9920
CAS:62645-28-7
Package:250Mg,25Mg More... - CB Index:76
- Related Information:Catalog(96815)
- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:Ro 106-9920;6-(Phenylsulfinyl)tetrazolo[1,5-b]pyridazine
CAS:62645-28-7
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
- Related Information:Catalog(15848)
- Company Name:Shenzhen Polymeri Biochemical Technology Co., Ltd.
- Tel:+86-400-002-6226 13028896684
- Products Intro:Product Name:Ro 106-9920
CAS:62645-28-7
More... - CB Index:58
- Related Information:Catalog(56060)
- Company Name:MedBioPharmaceutical Technology Inc
- Tel:021-69568360 18916172912
- Products Intro:Product Name:RO 106-9920
CAS:62645-28-7
Purity:98% Package:10mg; 50mg Remarks:Medbio - CB Index:58
- Related Information:Catalog(8141)