Basic information Supplier

CARBENICILLIN INDANYL SODIUM

Basic information Supplier
26605-69-6 Basic informationMore
USE
<p>Carbenicillin indanyl sodium has been shown to reduce blood pressure in mammals and also has been used as a β-lactam antibiotic.<br/> Efforts to obtain orally active forms of carbenicillin led to theeventual release of the 5-indanyl ester carbenicillin indanyl,6-[2-phenyl-2-(5-indanyloxycarbonyl)acetamido]penicillanicacid (Geocillin), in 1972. Approximately 40% of theusual oral dose of indanyl carbenicillin is absorbed. After absorption,the ester is hydrolyzed rapidly by plasma and tissueesterases to yield carbenicillin. Thus, although the highlylipophilic and highly protein-bound ester has in vitro activitycomparable with that of carbenicillin, its activity in vivo isdue to carbenicillin. Indanyl carbenicillin thus provides anorally active alternative for the treatment of carbenicillinsensitivesystemic and urinary tract infections caused byPseudomonas spp., indole-positive Proteus spp., and selectedspecies of Gram-negative bacilli.<br>Clinical trials with indanyl carbenicillin revealed a relativelyhigh frequency of GI symptoms (nausea, occasionalvomiting, and diarrhea). It seems doubtful that the highdoses required for the treatment of serious systemic infectionscould be tolerated by most patients. Indanyl carbenicillinoccurs as the sodium salt, an off-white, bitter powderthat is freely soluble in water. It is stable in acid. It should beprotected from moisture to prevent hydrolysis of the ester.</p>

Browse by Nationality 26605-69-6 Suppliers >Global suppliers

Beijing (2) Shanghai (4) Guangdong (1) Zhejiang (1) Hubei (1) Anhui (1) Shaanxi (1) Other (1) Member (11) All (12)
Please select the suppliers
Recommend You Select Member Companies
  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:010-82848833 400-666-7788
  • Products Intro:Product Name:SodiuM Indanylcarbinicillin
    CAS:26605-69-6
    Package:500Mg,50Mg More...
  • CB Index:76
  • Related Information:Catalog(96815)
  •  
  • Company Name:Beijing Solarbio Science & Tecnology Co., Ltd.
  • Tel:010-50973186 4009686088
  • Products Intro:CAS:26605-69-6
    Package:300mg More...
  • CB Index:68
  • Related Information:Catalog(18338)
  •  
  • Company Name:Shenzhen Polymeri Biochemical Technology Co., Ltd.
  • Tel:+86-400-002-6226 +86-13028896684;
  • Products Intro:Product Name:SodiuM Indanylcarbinicillin
    CAS:26605-69-6
    More...
  • CB Index:58
  • Related Information:Catalog(56902)
  •  
  • Company Name:AFINE CHEMICALS LIMITED
  • Tel:+86-0571-85134551
  • Products Intro:Product Name:CARBENICILLIN INDANYL SODIUM
    CAS:26605-69-6
    Purity:98%+ Package:Standard or custom package Remarks:excellent quality and reliable supplier
  • CB Index:58
  • Related Information:Catalog(15356)
  •  
  • Company Name:Shaanxi Dideu Medichem Co. Ltd
  • Tel:+86-029-89586680 +86-18192503167
  • Products Intro:Product Name:CARBENICILLIN INDANYL SODIUM USP/EP/BP
    CAS:26605-69-6
    Purity:99.9% Package:25kgs/Drum;200kgs/Drum Remarks:FDA GMP CEP Approved Manufacturer
  • CB Index:58
  • Related Information:Catalog(7724)
  •  
  • Company Name:Energy Chemical
  • Tel:021-58432009 400-005-6266
  • Products Intro:Product Name:Sodium Indanylcarbinicillin
    CAS:26605-69-6
    Purity:NULL Package:500mg;50mg Remarks:NULL
  • CB Index:58
  • Related Information:Catalog(44808)
  •  
  • Company Name:TargetMol Chemicals Inc.
  • Tel: 4008200310
  • Products Intro:Product Name:Carindacillin sodium
    CAS:26605-69-6
    Package:2mg/RMB 591;5mg/RMB 997;10mg/RMB 1730
  • CB Index:58
  • Related Information:Catalog(24648)
  •  
1 2