Vincristine sulfate
2068-78-2 Basic informationMore
- Product Name:Vincristine sulfate
- Synonyms: VINCRISTINE SULFATE VINCRISTINE SULFATE, APOCYNACEAE SPECIES VCR, LEUKOCRISTINE SULFATE VCR SULFATE Vincristine,Leurocristine,Oncovin,Vinblastine Vincristin Sulfate Vincristine sulfate,95% Vincaleukoblastine, 22-oxo-, sulfate (1:1)
- CAS:2068-78-2
- MF:C46H58N4O14S
- MW:923.04
- EINECS:218-190-0
- Mol File:2068-78-2.mol
-
USE
Vincristine sulfate is available as a 1-mg/mL solution in 1-,2-, and 5-mL vials for IV administration in acute leukemiaand as part of a multidrug regime for Hodgkin’s and neuroblastoma, Ewing sarcoma, Wilms tumor, soft tissuesarcoma, testicular cancer, liver cancer, and head and neckcancers. It has also been utilized in treating pediatric cancer.Vincristine is highly protein bound (75%) and may also bindto platelets that contain large amounts of tubulin. Numerousmetabolites have been detected and several have been identified,one of which is the 4-O-desacetyl derivative. The metabolismthat does occur is believed to largely be mediatedby CYP3A. Elimination occurs primarily in the bile with aterminal elimination half-life of 23 to 85 hours. The mostcommonly seen toxicity for vincristine is a dose-limitingneurotoxicity caused by effects on axonal microtubules.Symptoms are variable and include peripheral neuropathy,ataxia, seizure, bone pain, and coma. Constipation is also acommonly seen toxicity, and laxatives may be used prophylactically.Other toxicities include alopecia, skin rash, mildmyelosuppression, secretion of antidiuretic hormone,azospermia, and amenorrhea.
Lastest Price from Vincristine sulfate manufacturers
- Vincristine sulfate
-
- US $0.00 /Kg/Bag
- CAS:2068-78-2
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 100kgs
- 2025-02-06
- Vincristine Sulfate
-
- US $25.00 /kg
- CAS:2068-78-2
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 100tons
- 2025-01-16
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- Company Name:Guangzhou Isun Pharmaceutical Co., Ltd
- Tel:020-39119399 18927568969
- Products Intro:Product Name:Vincristine sulfate
CAS:2068-78-2
Purity:98% Package:1G; 5G; 25G; 100G; 1KG; 5KG More... - CB Index:55
- Related Information:Catalog(4674)
- Company Name:Shaanxi Pioneer Biotech Co.,Ltd
- Tel:029-86107037-8021 15353537425
- Products Intro:Product Name:Vincristine sulfate
CAS:2068-78-2
Purity:99% HPLC Package:1mg;10mg;1kg;10kg;25kg - CB Index:58
- Related Information:Catalog(203)
- Company Name:SHANDONG OCTAGON CHEMICALS LIMITED
- Tel:0535-15589503653 15589503653
- Products Intro:Product Name:Vincristine Sulfate; Vincristine Sulphate
CAS:2068-78-2
Purity:98%, 99% Package:1G, 10G, 100G, 500G, 1KG, 25KG Remarks:kg - CB Index:58
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- Company Name:Kono Chem Co.,Ltd
- Tel:029-86107037-8009 13279399072
- Products Intro:Product Name:Vincristine sulfate
CAS:2068-78-2
Purity:98% HPLC Remarks:10g - CB Index:58
- Related Information:Catalog(594)
- Company Name:HUBEI MICRO PHARMACEUTICAL
- Tel: 18627055345
- Products Intro:Product Name:Vincristine sulfate
CAS:2068-78-2
Purity:99% Package:10g;100g;1000g - CB Index:58
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- Company Name:Guangzhou Younan Technology Co., Ltd
- Tel:020-82000279 18988968278
- Products Intro:Product Name:Vincristine sulfate
CAS:2068-78-2
Purity:98% Package:5mg;10mg;50mg;100mg Remarks:g - CB Index:58
- Related Information:Catalog(4297)
- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:Vincristine sulfate, 98%, from Catharanthus roseus (L.) G. Don
CAS:2068-78-2
Purity:98% Package:10MG More... - CB Index:76
- Related Information:Catalog(96815)
- Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel:021-61259108 18621169109
- Products Intro:Product Name:Vincristine sulfate
CAS:2068-78-2
Purity:95% Remarks:20344 More... - CB Index:62
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