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Apalutamide

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956104-40-8 Basic informationMore
USE
ARN-509 (10 mg/kg/d, oral) inhibits tumor growth with decreased proliferative index and increased apoptotic rate in castrate male immunodeficient mice harboring LNCaP/AR-luc xenograft tumors. ARN-509 dose dependently inhibits tumor growth with highest efficacy at dose of 30 mg/kg/day in castrate male immunodeficient mice harboring LNCaP/AR-luc xenograft tumors. ARN-509 dosed at 10 mg/kg/d for 28 days results in a 3-fold reduction in prostates weight associated with lacking glandular secretory activity and 1.7-fold reduction in epididymis weight in adult male dogs. ARN-509 (10 mg/kg/d, oral) inhibits cell proliferation of prostate tissues in adult male dogs. ARN-509 is safe and well tolerated in 24 patients with metastatic CRPC who has progressed on prior treatments and peak plasma concentrations occurred 2 to 3 hours after administration. ARN-509 results in durable PSA declines at doses ranging from 30 to 300 mg in patients with metastatic CRPC. ARN-509 shows powerful anti-cancer activity and induces durable remissions long after therapy completion in castrate resistant prostate cancer mouse models.
Lastest Price from Apalutamide manufacturers
  • ARN-509
  • US $1.00 /g
  • CAS:956104-40-8
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 100kg
  • 2024-05-07
  • Apalutamide
  • US $0.00 /Kg/Bag
  • CAS:956104-40-8
  • Min. Order: 2Kg/Bag
  • Purity: 0.99
  • Supply Ability: 20 tons
  • 2024-04-28

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  • Company Name:Cangzhou Kangrui Medical Technology Co., LTD
  • Tel: 18632776803
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  • Company Name:ChemFuture PharmaTech (Jiangsu) Ltd
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  • Company Name:Changzhou Yongfeng Biomedicine Co. Ltd.
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  • Company Name:Hangzhou Xinbaisi Biomedical Co., Ltd.
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  • Company Name:Sichuan Qingmu Pharmaceutical Co., Ltd.
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    Purity:In-House; HPLC Package:1KG; 5KG;10KG
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  • Company Name:Junyu Chemexpress Co., Ltd.
  • Tel:0731-88036271 13723890100
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    Purity:99.50% Package:1g,25g,50g,100g,200g,500g,1kg,5kg
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  • Company Name:Shanghai Youna Biopharmaceutical Co., Ltd
  • Tel: 18164002430
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  • Company Name:Wuhan Yida Pharmaceutical Co., Ltd
  • Tel:+86-13401188533 +86-13476102740
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    Purity:99 Package:10g;100g;1000g
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