DIETHYLCARBAMAZINE

• Product Name:DIETHYLCARBAMAZINE
• Synonyms: 1-(N,N-Diethylcarbamyl)-4-methylpiperazine 1-Diethylcarbamoyl-4-Methylpiperazine 1-Diethylcarbamyl-4-methylpiperzine 1-Methyl-4-diethylcarbamoylpiperazine 1-Methyl-4-diethylcarbamylpiperazine 1-piperazinecarboxamide,N,N-diethyl-4-methyl- 84L Banocide
• CAS:90-89-1
• MF:C10H21N3O
• MW:199.29
• EINECS:202-023-3
• Mol File:90-89-1.mol
• 

Diethylcarbamazine (DEC) is a piperazine derivative which was introduced in clinical medicine in 1947. The drug is active against adult and microfilariae forms of Wuchereria bancrofti, Brugia malayi, Brugia timori and Loa loa. Against Onchocerca volvulus, the drug is only effective against the microfilariae. Soon after its administration, it causes rapid disappearance of microfilariae from the blood (lymphatic filariasis) or from the skin (onchocerciasis). Its effect against microfilariae in nodules or in hydroceles and in advanced elephantiasis is minimal ^[1].<br> The mechanism of action of DEC is not well understood. The drug has no microfilaricidal effect in vitro ^[2]. In vivo, the microfilariae is first immobilized by the drug due to a possible hyperpolarization of the worm. This is followed by changes on the outer surface of the microfilariae making them more susceptible to the host’s defence system^[3]. More recently, the drug has been reported to inhibit microtubule polymerization and disrupt preformed microtubule protein prepared from porcine brain in vitro ^[4]. The relevance of this action in the living parasite remains to be studied. A similar&nbsp;mechanism of action has been described for benzimidazoles (see Mebendazole, p. 78).

• n,n-diethyl-4-methyl-1-piperazinecarboxamide
• 
• US $0.00 /KG
• CAS:90-89-1
• Min. Order: 1KG
• Purity: 97.3%
• Supply Ability: 100 tons
• 2022-02-19

• DIETHYLCARBAMAZINE
• 
• US $1.10 /g
• CAS:90-89-1
• Min. Order: 1g
• Purity: 99.9%
• Supply Ability: 100 Tons Min
• 2021-06-19

• Company Name:Chengdu HappySyn Pharmaceutical Technology Co., Ltd.
• Tel:028-85114309 15881143215
• Products Intro:Product Name:N,N-Diethyl-4-methylpiperazine-1-carboxamide
  CAS:90-89-1
  Purity:95% Package:g-kg More...
• CB Index:55
• Related Information:Catalog(1734)

• Company Name:Bide Pharmatech Ltd.
• Tel:400-1647117 15221909166
• Products Intro:Product Name:N,N-Diethylcarbamazine
  CAS:90-89-1
  Purity:97% Package:250mg;1g;5g;10g;25g; More...
• CB Index:60
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• Company Name:Finetech Industry Limited
• Tel:027-87465837 19945049750
• Products Intro:Product Name:N,N-DIETHYL-4-METHYL-1-PIPERAZINECARBOXAMIDE
  CAS:90-89-1
  Purity:98% Package:1g,10g,25g,500g,1kg
• CB Index:58
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• Company Name:Shanghai Xingui Biotechnology Co., Ltd.
• Tel: 17501653715
• Products Intro:Product Name:DIETHYLCARBAMAZINE
  CAS:90-89-1
  Purity:97% Package:100g,500g,1kg,5kg，10kg，25kg……
• CB Index:58
• Related Information:Catalog(10033)

• Company Name:Hubei Jusheng Technology Co.,Ltd
• Tel:027-59599241 18871490274
• Products Intro:Product Name:DIETHYLCARBAMAZINE
  CAS:90-89-1
  Purity:99% HPLC Package:25KG;200KG;5KG;1KG;1T More...
• CB Index:58
• Related Information:Catalog(9972)

• Company Name:Shanghai YuanYe Biotechnology Co., Ltd.
• Tel:021-61312847; 18021002903
• Products Intro:Product Name:N,N-DIETHYL-4-METHYL-1-PIPERAZINECARBOXAMIDE
  CAS:90-89-1
  Purity:95% Package:5g
• CB Index:60
• Related Information:Catalog(27322)

• Company Name:Amadis Chemical Company Limited
• Tel:571-89925085
• Products Intro:Product Name:N,N-diethyl-4-methyl-1-piperazin-4-iumcarboxamide
  CAS:90-89-1
  Purity:0.97 Package:mgs,gs,kgs Remarks:A843666
• CB Index:58
• Related Information:Catalog(131980)