Avanafil
330784-47-9 Basic informationMore
- Product Name:Avanafil
- Synonyms: 4-[[(3-Chloro-4-Methoxyphenyl)Methyl] aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-N-(2-pyriMidinylMethyl)-5-pyriMidinecarboxaMide Avanafil 4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide avanfil (S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-yl avanafil:4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)-1-pyrrolidinyl)-n-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide: (s)-2-(2-hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylami (S)-4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2pyrimidinylmethyl)-5-pyrimidinecarboxamide (S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine 4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide
- CAS:330784-47-9
- MF:C23H26ClN7O3
- MW:483.95
- EINECS:000-000-0
- Mol File:330784-47-9.mol
USE
Avanafil (Zepeed) was approved by the Korean Health Ministry for the
treatment of erectile dysfunction (ED) in August 2011. Avanafil is a
highly selective type 5 phosphodiesterase (PDE5) inhibitor.
Avanafil is reported to be the most selective PDE5
inhibitor on the market. The onset of Tmax and half-life also varies among
the marketed PDE5 inhibitors. Sildenafil has a T<sub>max</sub> at 1 h and a half-life of
3–5 h. Vardenafil is somewhat similar with a T<sub>max</sub> of 0.6 h and a half-life of
4–6 h. Tadalafil has the longest half-life among the marketed drugs with a
half-life of 17 h. Avanafil has a fast onset of action reaching T<sub>max</sub> in 0.6 h
with a half-life of 1.2 h. A synthesis of avanafil (TA-1790) is described
in the patent literature. The main elimination route of avanafil
is through the bile and feces. Avanafil was also found to be reabsorbed
through enterohepatic recirculation.
Lastest Price from Avanafil manufacturers
- Avanafil
- US $1.00 /kg
- CAS:330784-47-9
- Min. Order: 0.10000000kg
- Purity: 99%
- Supply Ability: 200KG
- 2024-12-04
- Avanafil
- US $10.00 /ASSAYS
- CAS:330784-47-9
- Min. Order: 1ASSAYS
- Purity: 99%
- Supply Ability: 100kg
- 2024-12-04
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- Company Name:Shandong Wankang Biotechnology Co. , Ltd.
- Tel:131-7317-1119 13173171119
- Products Intro:Product Name:Avanafil
CAS:330784-47-9
Purity:99.5 Package:1kg/RMB 5000;100kg/RMB 4800;1000kg/RMB 4500 - CB Index:58
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- Company Name:Jinan Cheminn Chemicals Co., Ltd.
- Tel:531-67875205 15726170169
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Purity:99% Package:On Request More... - CB Index:60
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- Company Name:Taizhou Tongxin Bio-Tech Co., Ltd
- Tel:0523-18601685-898 18652728585
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Purity:99% More... - CB Index:60
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- Company Name:Jinan Hongwan Biotechnology Co., Ltd.
- Tel:0531-58767175 13220585822
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Purity:99% HPLC Package:5KG;1KG - CB Index:58
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- Company Name:Chengdu Aupone Pharmaceutical Co.,Ltd.
- Tel: 18980796919
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CAS:330784-47-9
Purity:99.60% Package:1kg;10kg;100kg - CB Index:58
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- Company Name:haerbinhake
- Tel: 18646366731
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CAS:330784-47-9
Purity:99% HPLC Package:1kg,5kg - CB Index:58
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- Company Name:Nanjing CoreTech Biomedical Co,.Ltd
- Tel:025-52880806 13770327895
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CAS:330784-47-9
Purity:98% HPLC Package:5KG;1KG More... - CB Index:58
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- Company Name:Chengdu Pengshengyue Pharmaceutical Technology Co. , Ltd.
- Tel:171-5642-2032 19587414261
- Products Intro:Product Name:Avanafil
CAS:330784-47-9
Purity:99 Package:1kg/RMB 5500;25kg/RMB 5000 - CB Index:58
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