denileukin diftitox

• Product Name:denileukin diftitox
• Synonyms: denileukin diftitox Dab(389)-il-2 Ly 335348 Ontak Unii-25E79B5ctm
• CAS:173146-27-5
• MF:
• MW:0
• EINECS:
• Mol File:Mol File
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Denileukin diftitox, recombinant, Ontak, is an example of adrug that acts like a Trojan horse. One part of the molecule isinvolved in recognition and binds selectively with the diseasedcell, and a highly toxic second part of the molecule effectsa kill. Denileukin diftitox is a fusion protein expressedby a recombinant strain of E. coli. <br/> The diphtheriatoxin inhibits cellular protein synthesis and the cells die.Malignant cells in certain leukemias and lymphomas, includingcutaneous T-cell lymphoma, express the high-affinityIL-2 receptor on their cell surfaces. It is these cells thatdenileukin diftitox targets.Denileukin diftitox is indicated for the treatment of persistentor recurrent cutaneous T-cell lymphoma whose malignantcells express the CD25 component of the IL-2 receptor.Denileukin diftitox is supplied as a frozen solution inwater for injection. It should be stored at 10°C or colder.It is suggested that the vials be thawed in a refrigerator at2°C to 8°C for less than 24 hours or at room temperature for1 to 2 hours. Prepared solutions should be used within6 hours. The drug is administered by IV infusion from a bagor through a syringe pump.

• Company Name:Henan Tianfu Chemical Co.,Ltd.
• Tel:+86-0371-55170693 +86-19937530512
• Products Intro:Product Name:denileukin diftitox
  CAS:173146-27-5
  Purity:99% Package:25KG;5KG;1KG
• CB Index:55
• Related Information:Catalog(21663)